Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.50 |
| ▸ | HTR2B | P41595 | 12/20 | 0.43 |
| ▸ | HTR2C | P28335 | 8/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29573820 | 0.86 | HRH2 (0.44) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL29574031 | 0.83 | HRH2 (0.40) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL29573470 | 0.83 | ADORA3 (0.62) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL29573875 | 0.82 | HRH2 (0.53) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL29574073 | 0.79 | HTR2B (0.51) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL29573609 | 0.78 | ADORA3 (0.41) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL31350105 | 0.74 | HTR2B (0.71) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL31350147 | 0.73 | HTR2B (0.70) | HRH2HTR5AADORA3ADORA1HTR2B | |
| SCHEMBL29574455 | 0.73 | ADORA3 (0.55) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL31350257 | 0.73 | HTR2B (0.71) | HRH2HTR5AADORA3ADORA1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196219-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | Biointervene, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040241-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | BIOINTERVENE, INC. (US) | 2022-02-24 | — | — | WO | disclosed |