SCHEMBL29574035

SCHEMBL29574035

O=c1oc(-c2ccccc2Br)nc2cccc(Cl)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 1.00
C1R P00736 5/20 0.71
KMT2A Q03164 2/20 0.63
PBRM1 Q86U86 1/20 0.55
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
HTT P42858 1/20 0.48
PRSS1 P07477 1/20 0.44
CTSG P08311 1/20 0.44
KLK7 P49862 1/20 0.44
KLK14 Q9P0G3 1/20 0.44
KLK5 Q9Y337 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9985824 1.00 ELANE (1.00) ELANEC1RKMT2APBRM1MAPT
SCHEMBL9984780 0.88 ELANE (1.00) ELANEC1RKMT2APBRM1MAPT
SCHEMBL4190607 0.83 ELANE (0.79) ELANEC1RKMT2APBRM1MAPT
SCHEMBL29849973 0.83 ELANE (1.00) ELANEC1RKMT2APBRM1MAPT
SCHEMBL9984683 0.83 ELANE (1.00) ELANEC1RKMT2APBRM1MEN1
SCHEMBL9984776 0.83 ELANE (1.00) ELANEC1RKMT2APBRM1MAPT
SCHEMBL20176382 0.80 ELANE (0.73) ELANEC1RKMT2APBRM1MAPT
SCHEMBL9986142 0.80 ELANE (1.00) ELANEC1RPBRM1PRSS1CTSG
SCHEMBL6246926 0.80 ELANE (0.73) ELANEC1RPBRM1MAPT
SCHEMBL10507270 0.79 ELANE (0.71) ELANEC1RKMT2APBRM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109561993-B Determination of wound condition 基因芯片有限公司 2022-05-10 CN disclosed