SCHEMBL9984683

SCHEMBL9984683

Cc1ccccc1-c1nc2cccc(Cl)c2c(=O)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 1.00
C1R P00736 3/20 0.71
PBRM1 Q86U86 1/20 0.62
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CASP3 P42574 1/20 0.50
RAB9A P51151 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9984780 0.88 ELANE (1.00) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL8006834 0.84 C1R (0.81) ELANEC1R
SCHEMBL29574035 0.83 ELANE (1.00) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL4190607 0.83 ELANE (0.79) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL9984776 0.83 ELANE (1.00) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL29849973 0.83 ELANE (1.00) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL9985824 0.83 ELANE (1.00) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL9986142 0.83 ELANE (1.00) ELANEC1RPBRM1
SCHEMBL20176382 0.80 ELANE (0.73) ELANEC1RPBRM1MEN1KMT2A
SCHEMBL8210844 0.80 ELANE (0.67) ELANEC1RPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110319611-A1 BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME CHANG GUNG UNIVERSITY (TW) 2011-12-29 US claimed
US-20110319611-A1 BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME CHANG GUNG UNIVERSITY (TW) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319611-A1 BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME CYP4X1, CYP2B6, CYP2C19 ELANE 3461/4885C1R 84/4885PBRM1 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.