Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 17/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 14/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 6/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29573875 | 0.90 | HRH2 (0.53) | HTR2BADORA1ADORA3HRH2HTR5A | |
| SCHEMBL31350147 | 0.86 | HTR2B (0.70) | HTR2BADORA1ADORA3HRH2HTR5A | |
| SCHEMBL31350105 | 0.84 | HTR2B (0.71) | HTR2BADORA1ADORA3HRH2HTR5A | |
| SCHEMBL31350257 | 0.84 | HTR2B (0.71) | HTR2BADORA1ADORA3HRH2HTR5A | |
| SCHEMBL29573781 | 0.82 | HTR2B (0.73) | HTR2BADORA1ADORA3HRH2HTR2C | |
| SCHEMBL29574455 | 0.81 | ADORA3 (0.55) | HTR2BADORA1ADORA3HTR2CADORA2A | |
| SCHEMBL29573969 | 0.79 | HRH2 (0.54) | HTR2BADORA1ADORA3HRH2HTR5A | |
| SCHEMBL29574436 | 0.78 | ADORA1 (0.57) | HTR2BADORA1ADORA3HTR2CSLC6A3 | |
| SCHEMBL31350070 | 0.77 | HTR2B (0.71) | HTR2BADORA1ADORA3HRH2HTR5A | |
| SCHEMBL19415065 | 0.77 | HTR2B (0.55) | HTR2BADORA1ADORA3HRH2HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196219-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | Biointervene, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040241-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | BIOINTERVENE, INC. (US) | 2022-02-24 | — | — | WO | disclosed |