Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | RET | P07949 | 9/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30548162 | 1.00 | GPR119 (0.46) | GPR119RETEGLN2PGGT1BMAP4K4 | |
| SCHEMBL24265827 | 1.00 | GPR119 (0.46) | GPR119RETEGLN2PGGT1BMAP4K4 | |
| SCHEMBL29642205 | 0.87 | GPR6 (0.39) | — | |
| SCHEMBL24266538 | 0.86 | GPR119 (0.49) | GPR119RETEGLN2PGGT1BMAP4K4 | |
| SCHEMBL30548172 | 0.86 | GPR119 (0.49) | GPR119RETEGLN2PGGT1BMAP4K4 | |
| SCHEMBL29574932 | 0.86 | GPR119 (0.49) | GPR119RETEGLN2PGGT1BMAP4K4 | |
| SCHEMBL24265819 | 0.81 | HRH3 (0.38) | — | |
| SCHEMBL24455367 | 0.80 | GPR119 (0.49) | GPR119RETEGLN2PGGT1BMAP4K4 | |
| SCHEMBL22932935 | 0.79 | GPR119 (0.48) | GPR119EGLN2PGGT1B | |
| SCHEMBL24265687 | 0.78 | CKS1B (0.53) | GPR119MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |