Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391614 | 0.87 | ACHE (0.50) | GPR119ACHEKIF18ACKS1BSKP1 | |
| SCHEMBL22932932 | 0.85 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL22933035 | 0.85 | GPR119 (0.53) | GPR119ACHECCNT1 | |
| SCHEMBL29826099 | 0.84 | GLP1R (0.53) | GPR119 | |
| SCHEMBL20266356 | 0.84 | GLP1R (0.53) | GPR119 | |
| SCHEMBL22933033 | 0.84 | KIF18A (0.54) | GPR119KIF18ATRPA1 | |
| SCHEMBL24574904 | 0.82 | GLP1R (0.51) | GPR119 | |
| SCHEMBL31025621 | 0.82 | GLP1R (0.51) | GPR119 | |
| SCHEMBL22932912 | 0.80 | DPP4 (0.46) | ACHE | |
| SCHEMBL24455367 | 0.80 | GPR119 (0.49) | GPR119CKS1BSKP1SKP2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018023-A1 | SMALL MOLECULE GLP-1 RECEPTOR MODULATOR | 济南泰达领创医药技术有限公司 | 2021-02-04 | — | — | WO | disclosed |