Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544081 | 0.79 | LMNA (0.37) | LMNASMN1; SMN2POLBSMYD3PTGDR2 | |
| SCHEMBL29515000 | 0.77 | SMYD3 (0.35) | LMNASMN1; SMN2POLBSMYD3PTGDR2 | |
| SCHEMBL31623568 | 0.76 | SMYD3 (0.45) | LMNASMN1; SMN2POLBSMYD3PTGDR2 | |
| SCHEMBL34473620 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2POLBPTGDR2HRH2 | |
| SCHEMBL22716158 | 0.75 | MTHFD2 (0.33) | — | |
| SCHEMBL22718639 | 0.74 | SMYD3 (0.33) | LMNASMN1; SMN2POLBSMYD3PTGDR2 | |
| SCHEMBL31623601 | 0.73 | SMYD3 (0.42) | LMNASMN1; SMN2POLBSMYD3PTGDR2 | |
| SCHEMBL11401965 | 0.73 | KDM4E (0.45) | LMNASMN1; SMN2PABPC1ATMKDM4E | |
| SCHEMBL7380124 | 0.72 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2POLBSMYD3PTGDR2 | |
| SCHEMBL1444915 | 0.72 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2POLBSMYD3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976613-A1 | AZEPINES AS HBV CAPSID ASSEMBLY MODULATORS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-04-06 | — | — | EP | disclosed |