Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254298 | 0.89 | TSHR (0.55) | ALDH1A1SMN1; SMN2KDM4EGPR35TSHR | |
| SCHEMBL71886 | 0.84 | GPR35 (0.60) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL29589123 | 0.84 | GPR35 (0.60) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL5738735 | 0.83 | HNF4A (0.58) | ALDH1A1SMN1; SMN2TSHRHNF4AHSP90AA1 | |
| SCHEMBL28745129 | 0.82 | GPR35 (0.58) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL1497989 | 0.80 | TSHR (0.60) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL27340096 | 0.79 | GPR35 (0.70) | ALDH1A1SMN1; SMN2CA1CA2HPGD | |
| SCHEMBL6672572 | 0.79 | TSHR (0.57) | ALDH1A1SMN1; SMN2KDM4EGPR35TSHR | |
| SCHEMBL29120750 | 0.79 | HNF4A (0.53) | ALDH1A1SMN1; SMN2TSHRHNF4AHSP90AA1 | |
| Salicylic Acid SCHEMBL29067256 | 0.79 | GPR35 (0.64) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638575-A | Method for preparing key intermediate of eltrombopag by one-pot method | 浙江国邦药业有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-110467531-B | Preparation method of 3 '-nitro-2' -hydroxybiphenyl-3-formic acid | 新发药业有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-119638575-A | Method for preparing key intermediate of eltrombopag by one-pot method | 浙江国邦药业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119638575-A | Method for preparing key intermediate of eltrombopag by one-pot method | 浙江国邦药业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-110467531-B | Preparation method of 3 '-nitro-2' -hydroxybiphenyl-3-formic acid | 新发药业有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-110467531-B | Preparation method of 3 '-nitro-2' -hydroxybiphenyl-3-formic acid | 新发药业有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-110467531-B | Preparation method of 3 '-nitro-2' -hydroxybiphenyl-3-formic acid | 新发药业有限公司 | 2022-04-19 | — | — | CN | disclosed |