Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.56 |
| ▸ | CKS1B | P61024 | 2/20 | 0.56 |
| ▸ | SKP1 | P63208 | 2/20 | 0.56 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265269 | 1.00 | GPR119 (0.56) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL23363145 | 0.89 | GPR119 (0.52) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL29990087 | 0.87 | GPR119 (0.51) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL24670625 | 0.87 | GPR119 (0.51) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL25224739 | 0.85 | ENPP2 (0.53) | CKS1BSKP1SKP2ACHEMAP4K4 | |
| SCHEMBL3108697 | 0.85 | HRH4 (0.46) | — | |
| SCHEMBL3111974 | 0.83 | CKS1B (0.54) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL29040783 | 0.83 | CKS1B (0.50) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL31181020 | 0.83 | CKS1B (0.54) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL24337896 | 0.83 | GPR119 (0.49) | GPR119CKS1BSKP1SKP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |