Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851155 | 1.00 | MPL (0.53) | MPLLDHACYP2D6TRPM4CDK2 | |
| SCHEMBL11507947 | 0.84 | MPL (0.58) | MPLLDHACYP2D6NSD2CASP6 | |
| SCHEMBL4810070 | 0.84 | MPL (0.58) | MPLLDHACYP2D6TRPM4CDK2 | |
| SCHEMBL9462532 | 0.82 | TTR (0.46) | MPLLDHACYP2D6IDO1NSD2 | |
| SCHEMBL7536504 | 0.82 | MPL (0.57) | MPLLDHACYP2D6TRPM4CDK2 | |
| SCHEMBL9300802 | 0.82 | LDHA (0.47) | MPLLDHACYP2D6TRPM4CDK2 | |
| SCHEMBL21874405 | 0.80 | BACE1 (0.50) | MPLLDHACYP2D6TRPM4CDK2 | |
| SCHEMBL14879315 | 0.79 | TSHR (0.50) | MPLLDHACYP2D6IDO1LMNA | |
| SCHEMBL2524546 | 0.77 | TSHR (0.48) | MPLLDHACYP2D6IDO1LMNA | |
| SCHEMBL31450788 | 0.76 | CYP2D6 (0.58) | MPLCYP2D6TRPM4NSD2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456958-B | Salt-tolerant pichia pastoris strain with azo dye degradation function, culture method and application thereof | 辽宁师范大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114456958-A | Salt-tolerant pichia guilliermondii strain with azo dye degradation function, culture method and application thereof | 辽宁师范大学 | 2022-05-10 | — | — | CN | disclosed |