Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462532 | 0.85 | TTR (0.46) | LDHAMPLHKDC1EP300HDAC3 | |
| SCHEMBL29575461 | 0.82 | MPL (0.53) | LDHAMPLHKDC1IDO1HSD17B10 | |
| SCHEMBL13851155 | 0.82 | MPL (0.53) | LDHAMPLHKDC1IDO1HSD17B10 | |
| SCHEMBL6938480 | 0.81 | TTR (0.55) | LDHAMPLAURKAAURKBALDH1A1 | |
| SCHEMBL7753514 | 0.80 | AURKA (0.54) | LDHAEP300HDAC3IDO1KAT2B | |
| SCHEMBL4810070 | 0.79 | MPL (0.58) | LDHAMPLHKDC1CDK2CYP2D6 | |
| SCHEMBL7536504 | 0.78 | MPL (0.57) | LDHAMPLHKDC1CDK2CYP2D6 | |
| SCHEMBL2981400 | 0.76 | LMNA (0.56) | LDHAHKDC1EP300HDAC3IDO1 | |
| SCHEMBL21874405 | 0.75 | BACE1 (0.50) | LDHAMPLHKDC1HSD17B10ALDH1A1 | |
| SCHEMBL547342 | 0.75 | CYP2D6 (0.54) | MPLAURKAAURKBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350838-A | Monoazo dyes | HOECHST CELANESE CORPORATION (US) | 1994-09-27 | — | — | US | disclosed |
| US-5350838-A | Monoazo dyes | HOECHST CELANESE CORPORATION (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1994018275-A1 | A HIGH TEMPERATURE PROCESS FOR PREPARING FIBER REACTIVE DYES | HOECHST CELANESE CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |
| WO-1994018275-A1 | A HIGH TEMPERATURE PROCESS FOR PREPARING FIBER REACTIVE DYES | HOECHST CELANESE CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |