Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 8/20 | 0.82 |
| ▸ | ULK1 | O75385 | 12/20 | 0.80 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.72 |
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.66 |
| ▸ | CDK7 | P50613 | 1/20 | 0.66 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17545058 | 1.00 | PTK2B (0.82) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17544613 | 0.95 | ULK1 (0.78) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17547508 | 0.95 | ULK1 (0.75) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17547579 | 0.95 | ULK1 (0.78) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17547502 | 0.93 | PTK2B (0.72) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17544983 | 0.92 | PTK2B (0.69) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17547505 | 0.91 | PTK2B (0.75) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17544995 | 0.91 | ULK1 (0.69) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17547573 | 0.91 | ULK1 (0.69) | PTK2BULK1PTK2CDK1CCNB1 | |
| SCHEMBL17547517 | 0.91 | PTK2B (0.68) | PTK2BULK1PTK2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3185868-B1 | NOVEL ULK1 INHIBITORS AND METHODS USING SAME | SALK INST FOR BIOLOGICAL STUDI (US) | 2022-04-06 | — | — | EP | disclosed |