Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219734 | 0.94 | PPARD (0.47) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL8993904 | 0.92 | LPAR3 (0.47) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL9701750 | 0.92 | LPAR3 (0.47) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL2955740 | 0.92 | LPAR3 (0.47) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL212199 | 0.87 | PPARD (0.52) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL2382263 | 0.81 | PPARD (0.50) | PPARDTSHRTDP1AOX1TP53 | |
| SCHEMBL9700826 | 0.80 | TP53 (0.41) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL9700821 | 0.80 | PPARD (0.53) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| SCHEMBL7268189 | 0.79 | PPARD (0.64) | PPARDTSHRTDP1TP53 | |
| SCHEMBL5017294 | 0.79 | PPARD (0.64) | PPARDTSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234985-B2 | Birefringent polymer brush structures formed by surface initiated ring-opening metathesis polymerization | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-01-12 | — | — | US | disclosed |
| US-20140049823-A1 | BIREFRINGENT POLYMER BRUSH STRUCTURES FORMED BY SURFACE INITIATED RING-OPENING METATHESIS POLYMERIZATION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-02-20 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060280719-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2006-12-14 | — | — | US | disclosed |
| US-7109184-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1485391-B1 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORP (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-1485391-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040019020-A1 | Phosphate transport inhibitors | GELTEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2003080630-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280719-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC43A1 | PPARD 3322/4885TSHR 76/4885LPAR2 1433/4885 |
| US-20040019020-A1 | Phosphate transport inhibitors | SLC34A2, SLC43A1, SLC34A1 | PPARD 3859/4885TSHR 194/4885LPAR2 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.