Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16443935 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL4772795 | 0.86 | ALDH1A1 (0.54) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL31392522 | 0.80 | ALDH1A1 (0.57) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL4275842 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL2742977 | 0.78 | ALDH1A1 (0.62) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL17806132 | 0.77 | ALDH1A1 (0.58) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL3800934 | 0.76 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL18188350 | 0.76 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL11815548 | 0.76 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL14414383 | 0.73 | ALDH1A1 (0.54) | ALDH1A1PDE10APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302878-A | Tyrosine kinase non-receptor 1(TNK1) inhibitors and uses thereof | 大日本住友制药肿瘤公司 | 2022-04-08 | — | — | CN | disclosed |