Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.78 |
| ▸ | EGFR | P00533 | 19/20 | 0.74 |
| ▸ | KDR | P35968 | 2/20 | 0.73 |
| ▸ | AURKA | O14965 | 1/20 | 0.73 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.73 |
| ▸ | INSR | P06213 | 1/20 | 0.73 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.73 |
| ▸ | FLT4 | P35916 | 1/20 | 0.73 |
| ▸ | CLK1 | P49759 | 1/20 | 0.73 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.73 |
| ▸ | TEK | Q02763 | 1/20 | 0.73 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577315 | 0.95 | FBP1 (0.78) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL28907231 | 0.95 | EGFR (0.84) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL5412843 | 0.95 | EGFR (0.84) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL15928080 | 0.91 | FBP1 (0.66) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL15217652 | 0.91 | FBP1 (0.78) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL30207668 | 0.91 | EGFR (0.85) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL28520911 | 0.91 | EGFR (0.85) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL14964773 | 0.91 | EGFR (0.85) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL31491085 | 0.91 | EGFR (0.85) | FBP1EGFRKDRAURKAERBB2 | |
| SCHEMBL15217656 | 0.90 | EGFR (0.90) | FBP1EGFRKDRAURKAERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069913-B | Bis (morpholinylalkoxy) quinazoline derivative and application thereof in anti-tumor aspect | 陕西师范大学 | 2022-03-01 | — | — | CN | disclosed |