Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.85 |
| ▸ | KDR | P35968 | 2/20 | 0.84 |
| ▸ | AURKA | O14965 | 1/20 | 0.84 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.84 |
| ▸ | INSR | P06213 | 1/20 | 0.84 |
| ▸ | FBP1 | P09467 | 1/20 | 0.84 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.84 |
| ▸ | FLT4 | P35916 | 1/20 | 0.84 |
| ▸ | CLK1 | P49759 | 1/20 | 0.84 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.84 |
| ▸ | TEK | Q02763 | 1/20 | 0.84 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964773 | 1.00 | EGFR (0.85) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL30207668 | 1.00 | EGFR (0.85) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL28520911 | 1.00 | EGFR (0.85) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL5412843 | 0.96 | EGFR (0.84) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL28907231 | 0.96 | EGFR (0.84) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL29577315 | 0.95 | FBP1 (0.78) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL14092460 | 0.94 | EGFR (0.92) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL13529196 | 0.93 | EGFR (0.98) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL5911655 | 0.93 | EGFR (0.86) | EGFRKDRAURKAERBB2INSR | |
| SCHEMBL30520472 | 0.93 | EGFR (0.87) | EGFRKDRAURKAERBB2INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152969-A | Compound capable of degrading epidermal growth factor receptor and application thereof | 普美瑞(苏州)生物科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025073251-A1 | COMPOUND CAPABLE OF DEGRADING EPIDERMAL GROWTH FACTOR RECEPTOR, AND USE THEREOF | 普美瑞(苏州)生物科技有限公司 | 2025-04-10 | — | — | WO | disclosed |