Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 13/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | GMNN | O75496 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | APEX1 | P27695 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299633 | 1.00 | PRKCA (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL6305111 | 1.00 | PRKCA (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL6298118 | 1.00 | PRKCA (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL149457 | 1.00 | PRKCA (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL29557297 | 1.00 | PRKCA (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL2335922 | 0.98 | PRKCA (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL2544854 | 0.98 | MEN1 (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL1008339 | 0.98 | PRKCA (0.97) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL29613054 | 0.98 | MEN1 (1.00) | PRKCAMEN1GMNNLMNAPOLB | |
| Dequalinium SCHEMBL34043 | 0.98 | MEN1 (1.00) | PRKCAMEN1GMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3806661-B1 | USE OF ANTAGONISTS OF T2R54 | FIRMENICH INCORPORATED (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4566459-A2 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | Firmenich Incorporated (US) | 2025-06-11 | — | — | EP | disclosed |
| US-12295396-B2 | Antagonists of T2R54 and compositions and uses thereof | FIRMENICH INCORPORATED (US) | 2025-05-13 | — | — | US | disclosed |
| US-20240114942-A1 | Antagonists of T2R54 and Compositions and Uses Thereof | FIRMENICH INCORPORATED (US) | 2024-04-11 | — | — | US | disclosed |
| US-11871772-B2 | Antagonists of T2R54 and compositions and uses thereof | FIRMENICH INCORPORATED (US) | 2024-01-16 | — | — | US | disclosed |
| EP-4165152-A1 | TEXTILE TREATMENT COMPOSITIONS | Enviro Specialty Chemicals Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| US-20220330591-A1 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11871772-B2 | Antagonists of T2R54 and compositions and uses thereof | TAS2R50, TAS2R30, TAS2R60 | PRKCA 2447/4885MEN1 4033/4885GMNN 1849/4885 |
| US-12295396-B2 | Antagonists of T2R54 and compositions and uses thereof | TAS2R50, TAS2R30, TAS2R60 | PRKCA 2447/4885MEN1 4033/4885GMNN 1849/4885 |
| US-20240114942-A1 | Antagonists of T2R54 and Compositions and Uses Thereof | TAS2R50, TAS2R30, TAS2R60 | PRKCA 2447/4885MEN1 4033/4885GMNN 1849/4885 |
| US-20220330591-A1 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | TAS2R50, TAS2R30, TAS2R60 | PRKCA 2447/4885MEN1 4033/4885GMNN 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.