Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dequalinium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.97 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.97 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.97 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.97 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.97 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | GMNN | O75496 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | APEX1 | P27695 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dequalinium SCHEMBL29613054 | 1.00 | MEN1 (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| Dequalinium SCHEMBL2544854 | 1.00 | MEN1 (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| Dequalinium SCHEMBL29380717 | 1.00 | MEN1 (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| Dequalinium SCHEMBL3967999 | 0.98 | MEN1 (0.97) | MEN1GMNNLMNAPOLBMAPT | |
| SCHEMBL6298118 | 0.98 | PRKCA (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| Dequalinium SCHEMBL29577841 | 0.98 | PRKCA (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| Dequalinium SCHEMBL149457 | 0.98 | PRKCA (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| SCHEMBL6299633 | 0.98 | PRKCA (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| Dequalinium SCHEMBL29557297 | 0.98 | PRKCA (1.00) | MEN1GMNNLMNAPOLBMAPT | |
| SCHEMBL6305111 | 0.98 | PRKCA (1.00) | MEN1GMNNLMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4338 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789979-B | Multi-arm polymers comprising free radical polymerizable monomers | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2026-05-26 | — | — | CN | claimed |
| US-20260137711-A1 | COMBINATION THERAPY FOR CANCER | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2026-05-21 | — | — | US | claimed |
| EP-4532035-B1 | GRANULES OF CLAY-BASED ANTIMICROBIAL PARTICLES | UNILEVER IP HOLDINGS B V (NL) | 2026-04-08 | — | — | EP | claimed |
| EP-4532036-B1 | SPHERICAL GRANULES OF CLAY-BASED ANTIMICROBIAL PARTICLES | UNILEVER IP HOLDINGS B V (NL) | 2026-03-04 | — | — | EP | claimed |
| EP-4171478-B1 | COMPOSITIONS COMPRISING ZINC AND ANTIMICROBIAL AGENT | UNILEVER IP HOLDINGS B V (NL) | 2025-08-06 | — | — | EP | claimed |
| US-12377047-B2 | Emulsions for treating mucous membrane infections | PROFEM GMBH (AT) | 2025-08-05 | — | — | US | claimed |
| EP-3291673-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR REDUCING MICROBIAL CONTAMINATION | POLYVATION B V (NL) | 2025-07-23 | — | — | EP | claimed |
| EP-4249494-B1 | A DRUG COMPRISING A RADICAL GENERATING CATALYST | ACENET INC (JP) | 2025-07-16 | — | — | EP | claimed |
| CN-117126656-B | Salt-tolerant nanoparticle stability-enhancing foam oil displacement system and preparation method thereof | 陕西延长石油（集团）有限责任公司 | 2025-06-24 | — | — | CN | claimed |
| CN-120000600-A | Dequindox ammonium chloride lozenge as well as preparation method and application thereof | 华润双鹤药业股份有限公司 | 2025-05-16 | — | — | CN | claimed |
| EP-0617611-A1 | ORAL OSMOTIC DEVICE. | ALZA CORP (US) | 1994-10-05 | — | — | EP | claimed |
| EP-0399479-B1 | CHEWING GUM FOR THE DISINFECTION OF THE MOUTH AND THE THROAT AND PROCESS FOR ITS PREPARATION | Gergely, Gerhard, Dr. (AT) | 1993-08-11 | — | — | EP | claimed |
| WO-1993011748-A1 | ORAL OSMOTIC DEVICE | ALZA CORPORATION (US) | 1993-06-24 | — | — | WO | claimed |
| US-5200194-A | Oral osmotic device | ALZA CORPORATION (US) | 1993-04-06 | — | — | US | claimed |
| EP-0151203-B1 | ANTI-PLAQUE DENTURE CLEANSING TABLET | Richardson GmbH (DE) | 1989-08-16 | — | — | EP | claimed |
| US-4523589-A | INHALATION THROUGH NASAL PASSAGES | VIRAL RESPONSE SYSTEMS, INC., A DE. CORP. | 1985-06-18 | — | — | US | claimed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | claimed |
| US-4321257-A | Potentiated medicaments | JOHNSON & JOHNSON (US) | 1982-03-23 | — | — | US | claimed |
| US-4294852-A | WATER, AN ALIPHATIC ALCOHOL AND AN ORGANIC ACID TO ADJUST THE PH OF THE VEHICLE | JOHNSON & JOHNSON (US) | 1981-10-13 | — | — | US | claimed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | claimed |