Methylmalonic Acid

Methylmalonic Acid

SCHEMBL29577852

CC(C(=O)O)C(=O)O.N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.51
FAAH O00519 2/20 0.49
LTA4H P09960 2/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
SLC7A5 Q01650 1/20 0.49
NOD1 Q9Y239 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9628000 0.93 ACE (0.58) ACENAALAD2FAAHLTA4HALPI
SCHEMBL18222588 0.93 ACE (0.58) ACENAALAD2FAAHLTA4HALPI
SCHEMBL161657 0.93 ACE (0.58) ACENAALAD2FAAHLTA4HALPI
SCHEMBL161658 0.93 ACE (0.58) ACENAALAD2FAAHLTA4HALPI
SCHEMBL15345879 0.90 LTA4H (0.62) ACELTA4H
D-Glutamate SCHEMBL4387193 0.90 NAALAD2 (0.64) ACENAALAD2LTA4HALPIPKM
Glutamic Acid SCHEMBL4387195 0.90 NAALAD2 (0.64) ACENAALAD2LTA4HALPIPKM
SCHEMBL30803739 0.84 NAALAD2 (0.61) ACENAALAD2
SCHEMBL8138539 0.84 ACE (0.63) ACENAALAD2FAAH
SCHEMBL14900078 0.84 ACE (0.63) ACENAALAD2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114373510-B Metabolic marker for diagnosing or monitoring lung cancer and screening method and application thereof 武汉迈特维尔医学科技有限公司 2023-12-01 CN disclosed
CN-114373510-A Metabolic marker for lung cancer diagnosis or monitoring and screening method and application thereof 武汉迈特维尔生物科技有限公司 2022-04-19 CN disclosed