Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388459 | 0.92 | BACE1 (0.57) | LTA4HMMEMMP2MMP7MMP9 | |
| SCHEMBL18222588 | 0.91 | ACE (0.58) | LTA4HACEMME | |
| SCHEMBL161657 | 0.91 | ACE (0.58) | LTA4HACEMME | |
| SCHEMBL161658 | 0.91 | ACE (0.58) | LTA4HACEMME | |
| SCHEMBL9628000 | 0.91 | ACE (0.58) | LTA4HACEMME | |
| SCHEMBL15345875 | 0.91 | FOLH1 (0.67) | LTA4HACEMMEFOLH1 | |
| Methylmalonic Acid SCHEMBL29577852 | 0.90 | ACE (0.52) | LTA4HACE | |
| Glutamic Acid SCHEMBL4387195 | 0.87 | NAALAD2 (0.64) | LTA4HACEMMEFOLH1 | |
| D-Glutamate SCHEMBL4387193 | 0.87 | NAALAD2 (0.64) | LTA4HACEMMEFOLH1 | |
| SCHEMBL13585297 | 0.85 | NOD1 (0.58) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164977-B1 | BIOMARKERS FOR PRE-DIABETES AND METHODS USING THE SAME | METABOLON INC (US) | 2013-10-30 | — | — | EP | disclosed |