Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489164 | 1.00 | MAPT (0.50) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24489140 | 0.93 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24488991 | 0.92 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24488924 | 0.89 | ADRB2 (0.52) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL29577885 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24489110 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL29578128 | 0.89 | MAPT (0.56) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24489097 | 0.89 | MAPT (0.56) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24488966 | 0.88 | HDAC8 (0.59) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL24490524 | 0.86 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ERAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |