Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968632 | 0.91 | FFAR1 (0.44) | SOD1FFAR1PPARGPPARDALDH1A1 | |
| SCHEMBL10064534 | 0.89 | FFAR1 (0.43) | SOD1FFAR1PPARGPPARDALDH1A1 | |
| SCHEMBL232151 | 0.86 | FFAR1 (0.48) | FFAR1 | |
| SCHEMBL2935044 | 0.86 | FFAR1 (0.47) | SOD1FFAR1PPARGPPARDALDH1A1 | |
| SCHEMBL2975161 | 0.85 | FFAR1 (0.42) | FFAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3035594 | 0.81 | FFAR1 (0.46) | FFAR1PPARGPPARDALDH1A1FAAH | |
| SCHEMBL2977034 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL232971 | 0.78 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL10064536 | 0.78 | CYP2D6 (0.39) | FFAR1PPARGALDH1A1TNF | |
| SCHEMBL2918902 | 0.77 | FFAR1 (0.52) | SOD1FFAR1PPARGPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |