Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064534 | 0.96 | FFAR1 (0.43) | FFAR1PPARGPPARDFFAR4SOD1 | |
| SCHEMBL2957874 | 0.91 | SOD1 (0.38) | FFAR1PPARGPPARDSOD1ALDH1A1 | |
| SCHEMBL3035594 | 0.91 | FFAR1 (0.46) | FFAR1PPARGPPARDFFAR4ALDH1A1 | |
| SCHEMBL2918902 | 0.87 | FFAR1 (0.52) | FFAR1PPARGPPARDFFAR4SOD1 | |
| SCHEMBL2946459 | 0.86 | FFAR1 (0.54) | FFAR1FFAR4ALDH1A1TSHR | |
| SCHEMBL2965353 | 0.86 | FFAR1 (0.49) | FFAR1PPARDFFAR4ALDH1A1TSHR | |
| SCHEMBL2925885 | 0.85 | FFAR1 (0.53) | FFAR1PPARGPPARDFFAR4SOD1 | |
| SCHEMBL10078103 | 0.85 | FFAR1 (0.50) | FFAR1PPARGPPARDFFAR4SOD1 | |
| SCHEMBL232971 | 0.85 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL2947118 | 0.85 | FFAR1 (0.48) | FFAR1FFAR4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |