Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 5/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.47 |
| ▸ | CALCR | P30988 | 5/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031580 | 0.89 | CXCR4 (0.47) | CXCR4RAMP3CALCRAPLNR | |
| SCHEMBL31593304 | 0.87 | APLNR (0.47) | CXCR4APLNROPRM1OPRK1 | |
| SCHEMBL28356821 | 0.87 | CXCR4 (0.47) | CXCR4APLNROPRM1 | |
| SCHEMBL30275450 | 0.86 | CXCR4 (0.46) | CXCR4APLNR | |
| SCHEMBL31655163 | 0.86 | CXCR4 (0.47) | CXCR4RAMP3CALCRAPLNR | |
| SCHEMBL30065432 | 0.85 | APLNR (0.49) | CXCR4APLNROPRM1OPRK1 | |
| SCHEMBL29374733 | 0.85 | CXCR4 (0.45) | CXCR4APLNR | |
| SCHEMBL29474445 | 0.85 | RAMP3 (0.50) | CXCR4RAMP3CALCR | |
| SCHEMBL29496425 | 0.85 | RAMP3 (0.49) | RAMP3CALCR | |
| SCHEMBL31462089 | 0.84 | CXCR4 (0.46) | CXCR4APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | CXCR4 242/4885RAMP3 1081/4885CALCR 150/4885 |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | VIP, PTMS, IAPP | CXCR4 242/4885RAMP3 1081/4885CALCR 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.