SCHEMBL30065432

SCHEMBL30065432

CC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.49
▸ OPRM1 P35372 6/20 0.47
▸ OPRK1 P41145 6/20 0.47
▸ IL23R Q5VWK5 3/20 0.46
▸ CXCR4 P61073 4/20 0.45
▸ TFPI P10646 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30275450 0.93 CXCR4 (0.46) APLNRCXCR4
SCHEMBL28356821 0.89 CXCR4 (0.47) APLNROPRM1CXCR4
SCHEMBL29374733 0.88 CXCR4 (0.45) APLNRCXCR4
SCHEMBL31655163 0.87 CXCR4 (0.47) APLNRCXCR4
SCHEMBL29628862 0.87 IL23R (0.48) APLNROPRM1OPRK1IL23RCXCR4
SCHEMBL24202254 0.86 APLNR (0.46) APLNROPRM1OPRK1IL23RCXCR4
SCHEMBL30887061 0.86 CXCR4 (0.41) OPRM1CXCR4
SCHEMBL29579268 0.85 CXCR4 (0.48) APLNROPRM1OPRK1CXCR4
SCHEMBL31655138 0.85 NMUR2 (0.43) OPRM1CXCR4
SCHEMBL30887066 0.84 CXCR4 (0.45) CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320251-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING NOVEL CYCLIC PEPTIDES LISATA THERAPEUTICS INC (US) 2025-10-16 — — US disclosed
US-12351653-B1 Pharmaceutical compositions comprising novel cyclic peptides LISATA THERAPEUTICS, INC. 2025-07-08 — — US disclosed
US-20250144169-A1 iRGD-ANALOGS AND RELATED THERAPEUTIC METHODS LISATA THERAPEUTICS INC (US) 2025-05-08 — — US disclosed
EP-4333897-A1 IRGD-ANALOGS AND RELATED THERAPEUTIC METHODS Cend Therapeutics, Inc. (US) 2024-03-13 — — EP disclosed
US-20230201303-A1 METHODS FOR TREATING PANCREATIC CANCER AND OTHER SOLID TUMORS LISATA THERAPEUTICS, INC. 2023-06-29 — — US disclosed
CN-115867317-A Methods for treating pancreatic cancer and other solid tumors 澳大利亚药品中心私人有限公司 2023-03-28 — — CN disclosed
EP-4146274-A1 METHODS FOR TREATING PANCREATIC CANCER AND OTHER SOLID TUMORS Drugcendr Australia Pty Ltd. (AU) 2023-03-15 — — EP disclosed
US-20230050515-A1 iRGD-ANALOGS AND RELATED THERAPEUTIC METHODS LISATA THERAPEUTICS, INC. 2023-02-16 — — US disclosed
WO-2022235852-A1 IRGD-ANALOGS AND RELATED THERAPEUTIC METHODS CEND THERAPEUTICS, INC. (US) 2022-11-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320251-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING NOVEL CYCLIC PEPTIDES VIP, NGLY1, GRPR APLNR 41/4885OPRM1 1959/4885OPRK1 1345/4885
US-12351653-B1 Pharmaceutical compositions comprising novel cyclic peptides VIP, NGLY1, GRPR APLNR 41/4885OPRM1 1959/4885OPRK1 1345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback