Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987119 | 0.92 | GPR119 (0.44) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL30987047 | 0.92 | GPR119 (0.44) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL26782096 | 0.90 | GAA (0.39) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL28989395 | 0.90 | GAA (0.39) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL29579552 | 0.87 | GAA (0.38) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL29579997 | 0.87 | RORC (0.40) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL28712137 | 0.87 | GAA (0.39) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL31536742 | 0.87 | STS (0.41) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL28709747 | 0.87 | USP30 (0.38) | KLK7PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL31536752 | 0.86 | GAA (0.41) | KLK7GAATHRBSMN1; SMN2KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114106005-A | Nitrile derivative as dipeptidyl peptidase 1 inhibitor and application thereof | 四川海思科制药有限公司 | 2022-03-01 | — | — | CN | disclosed |