Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121835 | 0.79 | KDM4E (0.40) | KDM4EHSD17B10GAACASP1CASP7 | |
| SCHEMBL2522181 | 0.79 | TP53 (0.50) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL2528490 | 0.79 | SRC (0.53) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL29577443 | 0.79 | SRC (0.53) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL5273872 | 0.79 | PSMB8 (0.51) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL1505464 | 0.75 | PSMB8 (0.48) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL29838710 | 0.75 | PSMB8 (0.48) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL22030047 | 0.75 | PSMB8 (0.54) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL593432 | 0.75 | KDM4E (0.57) | PSMB8PSMB5KDM4EHSD17B10GAA | |
| SCHEMBL29385493 | 0.75 | KDM4E (0.57) | PSMB8PSMB5KDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265157-A1 | MHC MULTIMER EXPRESSION CONSTRUCTS AND USES THEREOF | Repertoire Immune Medicines, Inc. | 2023-08-24 | — | — | US | disclosed |
| EP-4171751-A2 | MHC MULTIMER EXPRESSION CONSTRUCTS AND USES THEREOF | Repertoire Immune Medicines, Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-4126923-A2 | BARCODABLE EXCHANGEABLE PEPTIDE-MHC MULTIMER LIBRARIES | Repertoire Immune Medicines, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| WO-2022087154-A1 | MHC CLASS II PEPTIDE MULTIMERS AND USES THEREOF | Repertoire Immune Medicines, Inc. (US) | 2022-04-28 | — | — | WO | disclosed |