Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | SLC26A3 | P40879 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522181 | 0.89 | TP53 (0.50) | KDM4EHSD17B10PTGDR2TP53ALDH1A1 | |
| SCHEMBL29579782 | 0.79 | PSMB8 (0.45) | KDM4EHSD17B10GAACASP1CASP7 | |
| SCHEMBL6578104 | 0.75 | CA12 (0.49) | KDM4EHSD17B10GAAALDH1A1HPGD | |
| SCHEMBL3994327 | 0.73 | SRC (0.64) | KDM4EHSD17B10GAACASP1CASP7 | |
| SCHEMBL5085076 | 0.72 | TP53 (0.51) | KDM4EHSD17B10GAACASP1CASP7 | |
| SCHEMBL27593866 | 0.69 | EDNRA (0.62) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL21665556 | 0.67 | CYP3A4 (0.48) | KDM4EHSD17B10GAACASP1CASP7 | |
| SCHEMBL10794643 | 0.67 | MAPT (0.52) | KDM4EHSD17B10GAACASP1CASP7 | |
| SCHEMBL3609409 | 0.67 | RAB9A (0.72) | KDM4EHSD17B10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4100411 | 0.66 | CYP3A4 (0.48) | KDM4EHSD17B10GAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029823-A1 | COMBINATORIAL PROTEASE SUBSTRATE LIBRARIES | IRM LLC (BM) | 2003-04-10 | — | — | WO | claimed |
| US-20030059847-A1 | Combinatorial protease substrate libraries | IRM, LLC (BM) | 2003-03-27 | — | — | US | claimed |