Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 4/20 | 0.74 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858189 | 1.00 | KAT2B (0.74) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL4863416 | 0.96 | KAT2B (0.72) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL29377506 | 0.91 | KAT2B (0.69) | KAT2BHCAR3MAPTALDH1A1TSHR | |
| SCHEMBL24076 | 0.91 | KAT2B (0.69) | KAT2BHCAR3MAPTALDH1A1TSHR | |
| SCHEMBL7970570 | 0.86 | KAT2B (0.71) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL14906561 | 0.85 | KAT2B (0.74) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL29416813 | 0.85 | KAT2B (1.00) | KAT2BPRSS1MAPTALDH1A1POLB | |
| SCHEMBL10113238 | 0.85 | KAT2B (1.00) | KAT2BPRSS1MAPTALDH1A1POLB | |
| SCHEMBL4640284 | 0.84 | KAT2B (0.64) | KAT2BHCAR3MAPTALDH1A1TSHR | |
| SCHEMBL16151564 | 0.84 | KAT2B (0.72) | KAT2BHCAR3PRSS1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232438-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | The Governors of the University of Alberta (CA) | 2023-08-30 | — | — | EP | disclosed |
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022082305-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-04-28 | — | — | WO | disclosed |