Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.72 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580274 | 0.96 | KAT2B (0.74) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL4858189 | 0.96 | KAT2B (0.74) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL29377506 | 0.90 | KAT2B (0.69) | KAT2BHCAR3MAPTALDH1A1TSHR | |
| SCHEMBL24076 | 0.90 | KAT2B (0.69) | KAT2BHCAR3MAPTALDH1A1TSHR | |
| SCHEMBL14906561 | 0.87 | KAT2B (0.74) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL16151564 | 0.86 | KAT2B (0.72) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL7970570 | 0.84 | KAT2B (0.71) | KAT2BHCAR3PRSS1MAPTTHRB | |
| SCHEMBL10113238 | 0.84 | KAT2B (1.00) | KAT2BPRSS1MAPTALDH1A1LMNA | |
| SCHEMBL29416813 | 0.84 | KAT2B (1.00) | KAT2BPRSS1MAPTALDH1A1LMNA | |
| SCHEMBL4640284 | 0.83 | KAT2B (0.64) | KAT2BHCAR3MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-1568355-A1 | N-alkylhydroxilated secondary paraphenylenediamine which is ortho- and/or meta substituted, composition for dying keratinous fibres comprising this paraphenylenediamine, methods based on this composition and uses. | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | KRT18, CDC73, TYR | KAT2B 785/4885HCAR3 2647/4885PRSS1 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.