Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725410 | 0.92 | ALDH1A1 (0.72) | KAT2BSMN1; SMN2ALDH1A1NPSR1RAD52 | |
| SCHEMBL17208819 | 0.86 | SMN1; SMN2 (0.69) | KAT2BSMN1; SMN2ALDH1A1NPSR1RAD52 | |
| SCHEMBL4858189 | 0.86 | KAT2B (0.74) | KAT2BALDH1A1TSHRTDP1MAPT | |
| SCHEMBL29580274 | 0.86 | KAT2B (0.74) | KAT2BALDH1A1TSHRTDP1MAPT | |
| SCHEMBL7973719 | 0.85 | ALDH1A1 (0.85) | KAT2BSMN1; SMN2ALDH1A1NPSR1RAD52 | |
| SCHEMBL1958474 | 0.85 | SMN1; SMN2 (0.67) | KAT2BSMN1; SMN2ALDH1A1NPSR1RAD52 | |
| SCHEMBL17678256 | 0.85 | SMN1; SMN2 (0.67) | KAT2BSMN1; SMN2ALDH1A1NPSR1RAD52 | |
| SCHEMBL4863416 | 0.84 | KAT2B (0.72) | KAT2BSMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL14906561 | 0.83 | KAT2B (0.74) | KAT2BSMN1; SMN2ALDH1A1KMT2ATDP1 | |
| SCHEMBL10113238 | 0.83 | KAT2B (1.00) | KAT2BSMN1; SMN2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |