SCHEMBL2958069

SCHEMBL2958069

CC1=Cc2ccc(Br)cc2C1c1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM1A O60341 5/20 0.32
KCNH2 Q12809 2/20 0.32
MAOB P27338 2/20 0.32
RCOR1 Q9UKL0 2/20 0.32
KDM1B Q8NB78 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.31
MAPK1 P28482 1/20 0.31
AGTR1 P30556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2969973 0.87 MEN1 (0.36) MEN1KMT2AKDM1A
SCHEMBL2971361 0.87 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM1A
SCHEMBL2959839 0.83 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2AKDM1A
SCHEMBL2963351 0.80 CYP2A6 (0.44) ALDH1A1MAPTMEN1KMT2AKDM1A
SCHEMBL2961226 0.80 SKP2 (0.40) ALDH1A1MAPK1
SCHEMBL2974766 0.79 RAPGEF4 (0.34) ALDH1A1
SCHEMBL17126935 0.76 MEN1 (0.34) ALDH1A1MAPTMEN1KMT2A
SCHEMBL2958072 0.75 TP53 (0.35) ALDH1A1MAPTMAPK1
SCHEMBL14212634 0.75 ALDH1A1 (0.44) ALDH1A1MAPTMEN1KMT2AMAOB
SCHEMBL2971669 0.73 HDAC4 (0.36) ALDH1A1MEN1KMT2AKDM1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 ALDH1A1 4332/4885MAPT 206/4885MEN1 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.