Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024470 | 0.80 | GAA (0.57) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL12727897 | 0.78 | GAA (0.55) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL9766726 | 0.75 | ALDH1A1 (0.53) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL18876419 | 0.71 | MAPT (0.49) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL18876416 | 0.71 | GAA (0.49) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL9143440 | 0.70 | NPC1 (0.47) | DPP4MEN1KMT2AMAPTERN1 | |
| SCHEMBL28606824 | 0.69 | NOTUM (0.48) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL7565683 | 0.69 | KMT2A (0.55) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL6550838 | 0.69 | SMN1; SMN2 (0.50) | GAAPOLBMEN1KMT2AMAPT | |
| SCHEMBL11835474 | 0.69 | TYMP (0.50) | GAAGFERPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-7763439-B2 | Two-photon absorbing dipyrrometheneboron difluoride dyes and their applications | ARCTIC DIAGNOSTICS OY (FI) | 2010-07-27 | — | — | US | disclosed |
| EP-1402263-B1 | TWO-PHOTON ABSORBING DIPYRROMETHENEBORON DIFLUORIDE DYES AND THEIR APPLICATIONS | ARCTIC DIAGNOSTICS OY (FI) | 2009-10-28 | — | — | EP | disclosed |
| US-20040157231-A1 | Two-photon absorbing dipyrromethenboron difluoride dyes and their applications | ARCTIC DIAGNOSTICS OY (FI) | 2004-08-12 | — | — | US | disclosed |
| EP-1402263-A1 | TWO-PHOTON ABSORBING DIPYRROMETHENEBORON DIFLUORIDE DYES AND THEIR APPLICATIONS | Arctic Diagnostics OY (FI) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003005030-A1 | TWO-PHOTON ABSORBING DIPYRROMETHENEBORON DIFLUORIDE DYES AND THEIR APPLICATIONS | ARCTIC DIAGNOSTICS OY (FI) | 2003-01-16 | — | — | WO | disclosed |
| EP-0612336-B1 | LONG WAVELENGTH CHEMICALLY REACTIVE DIPYRROMETHENEBORON DIFLUORIDE DYES AND CONJUGATES | MOLECULAR PROBES INC (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5451663-A | Fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0612336-A1 | LONG WAVELENGTH CHEMICALLY REACTIVE DIPYRROMETHENEBORON DIFLUORIDE DYES AND CONJUGATES | MOLECULAR PROBES, INC. (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5338854-A | Detectors for study of natural or synthetic lipid membranes | MOLECULAR PROBES, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| US-5274113-A | Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates | MOLECULAR PROBES, INC. (US) | 1993-12-28 | — | — | US | disclosed |
| WO-1993009185-A1 | LONG WAVELENGTH CHEMICALLY REACTIVE DIPYRROMETHENEBORON DIFLUORIDE DYES AND CONJUGATES | MOLECULAR PROBES, INC. (US) | 1993-05-13 | — | — | WO | disclosed |