Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578792 | 0.81 | DPP4 (0.42) | DPP4MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10528791 | 0.78 | CYP19A1 (0.36) | MAPTNFATC1GSK3BDYRK1ASLC6A2 | |
| SCHEMBL5458322 | 0.78 | SLC6A3 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17064513 | 0.78 | GRIN2B (0.35) | MAPTNFATC1GSK3BDYRK1ASLC6A2 | |
| SCHEMBL22694641 | 0.76 | DPP4 (0.52) | DPP4MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22983345 | 0.75 | CYP17A1 (0.33) | DPP4MAPTGRM8GRM4CYP19A1 | |
| SCHEMBL23006525 | 0.73 | KDM4D (0.35) | CYP19A1 | |
| SCHEMBL23006522 | 0.73 | KDM4D (0.35) | CYP19A1 | |
| SCHEMBL11680802 | 0.73 | IDO1 (0.42) | — | |
| SCHEMBL14785710 | 0.72 | DPP4 (0.44) | DPP4MAPTGSK3BSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |