Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790418 | 1.00 | MAPT (0.53) | MAPTALDH1A1CCR5POLBAKR1C3 | |
| SCHEMBL3658442 | 0.83 | ALDH1A1 (0.59) | MAPTALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL790291 | 0.81 | ALDH1A1 (0.58) | MAPTALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL12385911 | 0.81 | ALDH1A1 (0.69) | MAPTALDH1A1POLBAKR1C3SMN1; SMN2 | |
| SCHEMBL12499570 | 0.80 | IGF1R (0.46) | MAPTALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL30641872 | 0.80 | IGF1R (0.46) | MAPTALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL19496762 | 0.80 | ALDH1A1 (0.51) | MAPTALDH1A1AKR1C3SMN1; SMN2GAA | |
| SCHEMBL13718469 | 0.80 | MAPT (0.64) | MAPTALDH1A1CCR5AKR1C3SMN1; SMN2 | |
| SCHEMBL25464794 | 0.79 | ALDH1A1 (0.54) | MAPTALDH1A1AKR1C3SMN1; SMN2GAA | |
| SCHEMBL7057761 | 0.79 | HTR3A (0.61) | MAPTALOX15HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693503-A | Substituted pyrazine-2-carboxamides as HPK1 inhibitors for the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-106928162-B | Synthesis method of substituted N-phenyl morpholine compound | 韶远科技（上海)有限公司 | 2022-04-08 | — | — | CN | disclosed |