Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.58 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.57 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658442 | 0.98 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL30641872 | 0.83 | IGF1R (0.46) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL12499570 | 0.83 | IGF1R (0.46) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL15854543 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL790418 | 0.81 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7057761 | 0.81 | HTR3A (0.61) | MAPTMEN1KMT2AHTTALOX15 | |
| SCHEMBL29580955 | 0.81 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL21590283 | 0.80 | MAPT (0.48) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL4885809 | 0.80 | MAPT (0.68) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL16432438 | 0.79 | IGF1R (0.43) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |