Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | PRF1 | P14222 | 8/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017652 | 1.00 | LMNA (1.00) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL26779022 | 0.89 | LMNA (0.80) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL16836192 | 0.87 | MAPT (0.76) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL655727 | 0.84 | LMNA (0.72) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL30513606 | 0.84 | LMNA (0.72) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL19678702 | 0.84 | LMNA (0.72) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL26779021 | 0.84 | MAPT (0.71) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL6585715 | 0.81 | LMNA (0.68) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL30753590 | 0.81 | LMNA (0.68) | LMNAMAPTGAAPRF1MAOA | |
| SCHEMBL26779018 | 0.80 | MAPT (0.65) | LMNAMAPTGAAPRF1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| CN-116348109-B | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-119306730-A | Cyclic ether modified 3-cyano-4-arylaminoquinoline derivative as well as preparation method and application thereof | 河北医科大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-114751899-B | Diaryl urea mTOR kinase inhibitor, and pharmaceutical composition and application thereof | 贵州医科大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-111527084-B | Isofuranone compounds useful as HPK1 inhibitors | 百时美施贵宝公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-110225753-B | Process for preparing 5-phenoxy-1 (3H) isobenzofuranones | 金凯(辽宁)生命科技股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-114751899-A | Diaryl urea mTOR kinase inhibitor and pharmaceutical composition and application thereof | 贵州医科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-113045559-B | Diaryl urea PI3K alpha/mTOR double-target inhibitor and pharmaceutical composition and application thereof | 贵州医科大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-114315805-A | Aromatic ring-fused cyclic lactone thiohydantoin compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-04-12 | — | — | CN | disclosed |