Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 11/20 | 0.55 |
| ▸ | MAOB | P27338 | 10/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
| ▸ | PRF1 | P14222 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513606 | 1.00 | LMNA (0.72) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL2017652 | 0.84 | LMNA (1.00) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL29580985 | 0.84 | LMNA (1.00) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL12236613 | 0.81 | MAPT (0.53) | LMNAGAAMAPTMAPK14PRF1 | |
| SCHEMBL26779022 | 0.78 | LMNA (0.80) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL24102359 | 0.76 | MAOA (0.55) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL2257538 | 0.76 | MAOA (0.59) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL856120 | 0.76 | MAOB (0.62) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL854664 | 0.76 | MAOA (0.62) | LMNAGAAMAPTMAOAMAOB | |
| SCHEMBL1880049 | 0.76 | MAOA (0.55) | LMNAGAAMAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420576-A | Amino acid-like guided phthalide analogues and uses thereof | 河南农业大学 | 2024-08-02 | — | — | CN | claimed |
| CN-117285491-A | Amino acid-like guided phthalide analogues and uses thereof | 河南农业大学 | 2023-12-26 | — | — | CN | claimed |
| EP-2406250-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2015-08-12 | — | — | EP | claimed |
| US-20110230478-A1 | 4-Alkyl-substituted diaminopyrimidines | Bayer ScienceCrop AG (DE) | 2011-09-22 | — | — | US | claimed |
| CN-102123591-A | Diaminopyrimidines as plant protection agents | BAYER CROPSCIENCE AG | 2011-07-13 | — | — | CN | claimed |
| US-20110105472-A1 | Diaminopyrimidines as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | claimed |
| EP-2116547-A1 | Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | claimed |
| US-20260034238-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | GENMAB AS (DK) | 2026-02-05 | — | — | US | disclosed |
| US-20260007758-A1 | SOMATOSTATIN SUBTYPE-2 RECEPTOR (SST2R) NON-PEPTIDE DRUG CONJUGATES AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4648799-A1 | LIGAND-DRUG CONJUGATES | Sun Pharma Advanced Research Company Ltd (IN) | 2025-11-19 | — | — | EP | disclosed |
| US-12391727-B2 | Traceless reductively cleavable linker molecules for peptide purification | Gyros Protein Technologies AB (SE) | 2025-08-19 | — | — | US | disclosed |
| CN-119701683-B | Treatment system for preparing drinking water | 杭州水处理技术研究开发中心有限公司 | 2025-05-02 | — | — | CN | disclosed |
| US-12269845-B2 | Traceless reductively cleavable linker molecules for peptide purification | Gyros Protein Technologies AB (SE) | 2025-04-08 | — | — | US | disclosed |
| EP-0048539-A1 | Isoquinolyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-03-31 | — | — | EP | disclosed |
| US-4220357-A | PRESSURE SENSITIVE OR HEAT SENSITIVE SYSTEMS | STERLING DRUG INC. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4209618-A | COLOR PRECURSORS IN PRESSURE-SENSITIVE DUPLICATING SYSTEMS AND HEAT-SENSITIVE MARKING SYSTEMS | STERLING DRUG INC. (US) | 1980-06-24 | — | — | US | disclosed |
| US-4096176-A | Benzoylbenzoic acids | STERLING DRUG INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4094877-A | SUBSTITUTED 3,3-DIPHENYLPHTHALIDES AS COLOR PRECURSORS | STERLING DRUG INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4032527-A | COLOR PRECURSORS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-3953420-A | Azo pigments derived from 2-hydroxy-3-carboxynaphthalene containing a substituted or unsubstituted phthalimide | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391727-B2 | Traceless reductively cleavable linker molecules for peptide purification | VIP, NGLY1, HM13 | LMNA 829/4885GAA 705/4885MAPT 1722/4885 |
| US-12269845-B2 | Traceless reductively cleavable linker molecules for peptide purification | VIP, NGLY1, HM13 | LMNA 829/4885GAA 705/4885MAPT 1722/4885 |
| US-20110230478-A1 | 4-Alkyl-substituted diaminopyrimidines | DPM1, DPYD, POLR1C | LMNA 3131/4885GAA 781/4885MAPT 4144/4885 |
| US-20260007758-A1 | SOMATOSTATIN SUBTYPE-2 RECEPTOR (SST2R) NON-PEPTIDE DRUG CONJUGATES AND USES THEREOF | SSTR4, SSTR1, SSTR3 | LMNA 3261/4885GAA 3639/4885MAPT 4608/4885 |
| US-20110105472-A1 | Diaminopyrimidines as crop protection agents | DDX41, DDX1, DDX5 | LMNA 2286/4885GAA 1486/4885MAPT 4235/4885 |
| US-20260034238-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | MGAT3, GALE, GPI | LMNA 775/4885GAA 167/4885MAPT 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.