Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 7/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585889 | 0.87 | FFAR4 (0.37) | PARP1SCDSCD5CNR2TLR9 | |
| SCHEMBL24423119 | 0.87 | FFAR4 (0.37) | PARP1SCDSCD5CNR2TLR9 | |
| SCHEMBL29243367 | 0.83 | TLR8 (0.33) | PARP1TLR9TLR8TLR7PDE4B | |
| SCHEMBL24424507 | 0.83 | TLR8 (0.33) | PARP1TLR9TLR8TLR7PDE4B | |
| SCHEMBL24424506 | 0.83 | TLR8 (0.33) | PARP1TLR9TLR8TLR7PDE4B | |
| SCHEMBL29584400 | 0.83 | TLR8 (0.33) | PARP1TLR9TLR8TLR7PDE4B | |
| SCHEMBL29585034 | 0.83 | TLR8 (0.33) | PARP1TLR9TLR8TLR7PDE4B | |
| SCHEMBL29584316 | 0.83 | TLR8 (0.33) | PARP1TLR9TLR8TLR7PDE4B | |
| SCHEMBL29585365 | 0.83 | RAB9A (0.40) | HTR2ANPC1RAB9A | |
| SCHEMBL25090954 | 0.82 | TLR8 (0.36) | PARP1TLR9TLR8TLR7PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |