Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.57 |
| ▸ | UBE2M | P61081 | 1/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243426 | 1.00 | MGLL (0.57) | MGLLUBE2MDCUN1D1MALT1SMN1; SMN2 | |
| SCHEMBL29243469 | 0.90 | MGLL (0.53) | MGLLUBE2MDCUN1D1SMN1; SMN2KMT2A | |
| SCHEMBL29243779 | 0.89 | KDM5A (0.58) | MGLLKDM5ATRPV1TP53BP1 | |
| SCHEMBL29243869 | 0.86 | UBE2M (0.58) | UBE2MDCUN1D1SMN1; SMN2KMT2ATRPV1 | |
| SCHEMBL29243553 | 0.86 | UBE2M (0.58) | MGLLUBE2MDCUN1D1MALT1SMN1; SMN2 | |
| SCHEMBL29586579 | 0.86 | UBE2M (0.58) | MGLLUBE2MDCUN1D1MALT1SMN1; SMN2 | |
| SCHEMBL29584846 | 0.85 | KMT2A (0.51) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29243359 | 0.85 | KMT2A (0.51) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29243511 | 0.84 | POLB (0.52) | SMN1; SMN2KDM5A | |
| SCHEMBL29243873 | 0.83 | KMT2A (0.47) | UBE2MDCUN1D1KMT2AKDM5ATP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |