Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22381074 | 0.88 | CD274 (0.39) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL18483949 | 0.86 | CD274 (0.43) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL18485036 | 0.85 | CD274 (0.40) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL25232393 | 0.85 | CD274 (0.40) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL22816839 | 0.83 | CD274 (0.40) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL21646747 | 0.82 | CD274 (0.41) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL15519027 | 0.82 | CD274 (0.39) | CD274MEN1KMT2ACYP2C19CYP4F2 | |
| SCHEMBL31258838 | 0.81 | CD274 (0.39) | CD274MEN1KMT2A | |
| SCHEMBL14729661 | 0.80 | RAB9A (0.40) | CD274MEN1KMT2ANPC1RAB9A | |
| SCHEMBL31338368 | 0.80 | RXRA (0.45) | CD274MEN1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |