Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 12/20 | 0.41 |
| ▸ | RAB9A | P51151 | 12/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585365 | 0.86 | RAB9A (0.40) | NPC1RAB9AALPLHPGDSMN1; SMN2 | |
| SCHEMBL24423862 | 0.86 | RAB9A (0.41) | RAB9AHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL24424425 | 0.85 | NPC1 (0.42) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL30630493 | 0.83 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24422926 | 0.83 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30683708 | 0.77 | NPC1 (0.65) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL24423922 | 0.76 | KMT2A (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL29583326 | 0.76 | KMT2A (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL24423548 | 0.73 | KDM5A (0.51) | HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL24422914 | 0.73 | ALDH1A1 (0.39) | RAB9AHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |