Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936407 | 1.00 | EGFR (0.39) | EGFRKDM4ECASP6CA2CA12 | |
| SCHEMBL15720623 | 0.86 | CYP1A2 (0.36) | EGFRKDM4ECASP6SNCATSHR | |
| SCHEMBL23647876 | 0.86 | CA2 (0.33) | EGFRKDM4ECASP6CA2CA12 | |
| SCHEMBL30844586 | 0.86 | CYP1A2 (0.36) | EGFRKDM4ECASP6SNCATSHR | |
| SCHEMBL29790996 | 0.86 | CA2 (0.33) | EGFRKDM4ECASP6CA2CA12 | |
| SCHEMBL3484733 | 0.85 | BACE1 (0.39) | EGFRKDM4ECASP6CA2CA12 | |
| SCHEMBL21821384 | 0.85 | KDM4E (0.38) | EGFRKDM4ECASP6CA2CA12 | |
| SCHEMBL30808275 | 0.85 | KDM4E (0.38) | EGFRKDM4ECASP6CA2CA12 | |
| SCHEMBL20404242 | 0.85 | TRPA1 (0.43) | KDM4EMAPTSHBG | |
| SCHEMBL3484223 | 0.81 | CNR1 (0.37) | CA2SNCAMAPTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-114341103-B | Aminoguanhydrazones as retrograde transport stabilizers useful in the treatment of neurological diseases | 圣拉斐尔医院有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-114341103-A | Aminoguanidinohydrazones as reverse transporter stabilizers useful for the treatment of neurological disorders | 圣拉斐尔医院有限公司 | 2022-04-12 | — | — | CN | disclosed |