Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933853 | 0.86 | CYP4F2 (0.55) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL7313819 | 0.86 | CYP4F2 (0.55) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL29587114 | 0.84 | CYP4F2 (0.56) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL29588124 | 0.84 | ADAM17 (0.46) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL29586970 | 0.82 | CYP4F2 (0.58) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL24496702 | 0.80 | CYP4F2 (0.56) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL29588143 | 0.80 | CYP4F2 (0.56) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL29586780 | 0.80 | PPARG (0.54) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL7313848 | 0.80 | CYP4F2 (0.60) | CYP4F2CYP4A11PPARGPPARAPPARD | |
| SCHEMBL7313853 | 0.80 | CYP4F2 (0.60) | CYP4F2CYP4A11PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051931-A1 | HDAC INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-02-15 | — | — | US | disclosed |
| WO-2022120048-A1 | HDAC INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051931-A1 | HDAC INHIBITORS | HDAC8, HDAC1, HDAC2 | CYP4F2 4724/4885CYP4A11 3805/4885PPARG 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.