Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738811 | 1.00 | HTT (0.56) | HTTALDH1A1CYP1A2TSHRKMT2A | |
| SCHEMBL28738809 | 0.92 | ACACB (0.51) | HTTALDH1A1CYP1A2TSHRAURKA | |
| SCHEMBL17395307 | 0.89 | KMT2A (0.56) | HTTALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL29449949 | 0.88 | ALDH1A1 (0.57) | HTTALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28731691 | 0.88 | ALDH1A1 (0.57) | HTTALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL21630699 | 0.83 | KMT2A (0.52) | HTTALDH1A1CYP1A2TSHRKMT2A | |
| SCHEMBL31493850 | 0.83 | KMT2A (0.52) | HTTALDH1A1CYP1A2TSHRKMT2A | |
| SCHEMBL28731702 | 0.83 | KMT2A (0.52) | HTTALDH1A1CYP1A2TSHRKMT2A | |
| SCHEMBL15286477 | 0.81 | LMNA (0.55) | ALDH1A1TSHRLMNATAS1R3TAS1R1 | |
| SCHEMBL17395280 | 0.81 | LMNA (0.55) | HTTALDH1A1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380751-B | Indanamine derivatives, preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-114380751-A | Indane amine derivatives, preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |