SCHEMBL29587137

SCHEMBL29587137

O=C1CCC(Sc2ccc3cccnc3n2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.39
DDB1 Q16531 4/20 0.34
CRBN Q96SW2 4/20 0.34
PIM1 P11309 1/20 0.34
CYP1A2 P05177 1/20 0.33
GMNN O75496 1/20 0.31
TP53 P04637 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MMP2 P08253 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21047787 0.78 RXFP1 (0.42) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL29587162 0.78 RXFP1 (0.42) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL21047774 0.75 CRBN (0.54) ALDH1A1MEN1KMT2ADDB1CRBN
SCHEMBL29587012 0.71 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL21047745 0.71 CRBN (0.49) ALDH1A1KMT2ALMNADDB1CRBN
SCHEMBL28282312 0.71 DDB1 (0.33) MEN1KMT2ADDB1CRBNCYP1A2
SCHEMBL29586893 0.69 MEN1 (0.52) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL21047678 0.68 DDB1 (0.44) ALDH1A1LMNADDB1CRBNCYP3A4
SCHEMBL29586754 0.68 DDB1 (0.44) ALDH1A1LMNADDB1CRBNCYP3A4
SCHEMBL28282297 0.68 HPGD (0.45) ALDH1A1KMT2AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563016-B Method for producing perfluoroalkyl compound using monohydroperfluoroalkane as starting material 关东电化工业株式会社 2022-05-13 CN disclosed