SCHEMBL21047774

SCHEMBL21047774

O=C1CCC(Sc2ccccn2)CC1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 4/20 0.54
DDB1 Q16531 3/20 0.54
EHMT2 Q96KQ7 1/20 0.44
EHMT1 Q9H9B1 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
HCRTR2 O43614 1/20 0.42
ALDH1A1 P00352 4/20 0.38
KMT2A Q03164 3/20 0.38
GPR119 Q8TDV5 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
ATM Q13315 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10640635 0.85 EHMT2 (0.54) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL15271518 0.82 EHMT2 (0.50) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL15271041 0.82 EHMT2 (0.50) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL15271760 0.80 EHMT2 (0.48) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL28455598 0.80 EHMT2 (0.48) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL12949631 0.80 EHMT2 (0.48) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL4675111 0.79 EHMT2 (0.47) CRBNDDB1EHMT2EHMT1APOBEC3G
SCHEMBL21047745 0.78 CRBN (0.49) CRBNDDB1ALDH1A1KMT2A
SCHEMBL28282312 0.78 DDB1 (0.33) CRBNDDB1KMT2AMEN1CYP1A2
SCHEMBL24483635 0.77 EHMT2 (0.45) CRBNDDB1EHMT2EHMT1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495341-B1 PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL KANTO DENKA KOGYO KK (JP) 2022-11-02 EP disclosed
CN-109563016-B Method for producing perfluoroalkyl compound using monohydroperfluoroalkane as starting material 关东电化工业株式会社 2022-05-13 CN disclosed
US-10450253-B2 Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material KANTO DENKA KOGYO CO., LTD. (JP) 2019-10-22 US disclosed
EP-3495341-A1 METHOD FOR PRODUCING PERFLUOROALKYL COMPOUND USING MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL Kanto Denka Kogyo Co., Ltd. (JP) 2019-06-12 EP disclosed
US-20190169107-A1 PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2019-06-06 US disclosed
CN-109563016-A Using single hydrogen perfluoro alkane as the manufacturing method of the all-fluoroalkyl compound of starting material 关东电化工业株式会社 2019-04-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169107-A1 PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL PFKFB1, PFKFB4, PFAS CRBN 1845/4885DDB1 4487/4885EHMT2 774/4885
US-10450253-B2 Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material PFKFB1, PFKFB4, PFAS CRBN 1845/4885DDB1 4487/4885EHMT2 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.