Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305909 | 0.84 | KDM4E (0.55) | TSHRFOLH1KDM4EMAPTTHRB | |
| SCHEMBL3054458 | 0.84 | KDM4E (0.55) | TSHRFOLH1KDM4EMAPTTHRB | |
| SCHEMBL9382037 | 0.81 | FOLH1 (0.62) | FOLH1RIMKLANAALAD2GNPATFNTA | |
| SCHEMBL5437088 | 0.81 | FOLH1 (0.62) | FOLH1RIMKLANAALAD2GNPATFNTA | |
| SCHEMBL5437090 | 0.81 | FOLH1 (0.62) | FOLH1RIMKLANAALAD2GNPATFNTA | |
| SCHEMBL28421 | 0.81 | TSHR (0.47) | TSHRFOLH1RIMKLANAALAD2TGM2 | |
| SCHEMBL8185037 | 0.81 | TSHR (0.47) | TSHRFOLH1RIMKLANAALAD2TGM2 | |
| SCHEMBL15361783 | 0.79 | FOLH1 (0.60) | FOLH1RIMKLANAALAD2GNPATFNTA | |
| SCHEMBL32667918 | 0.78 | TSHR (0.43) | TSHRFOLH1RIMKLANAALAD2KDM4E | |
| SCHEMBL8185224 | 0.78 | KMT2A (0.47) | TSHRFOLH1RIMKLANAALAD2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12214086-B2 | Surface functionalized, host-guest polymer nano-assemblies and methods thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2025-02-04 | — | — | US | disclosed |
| EP-4240579-B1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2024-12-04 | — | — | EP | disclosed |
| US-11975499-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-05-07 | — | — | US | disclosed |
| EP-4240579-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022097049-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-05-12 | — | — | WO | disclosed |
| US-20220134692-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-05-05 | — | — | US | disclosed |
| US-20220133639-A1 | SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133639-A1 | SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF | MSN, CD44, EPHA2 | TSHR 2840/4885FOLH1 552/4885RIMKLA 1703/4885 |
| US-12214086-B2 | Surface functionalized, host-guest polymer nano-assemblies and methods thereof | MSN, CD44, EPHA2 | TSHR 2840/4885FOLH1 552/4885RIMKLA 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.