SCHEMBL28421

SCHEMBL28421

C=CC(=O)NC(CCC)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
TGM2 P21980 5/20 0.43
FPR2 P25090 1/20 0.43
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
NOD1 Q9Y239 1/20 0.40
CHRM1 P11229 1/20 0.40
AKR1A1 P14550 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MME P08473 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8185037 1.00 TSHR (0.47) TSHRTGM2FPR2FNTAFNTB
SCHEMBL1562504 0.89 TGM2 (0.50) TSHRTGM2NOD1HDAC2MME
SCHEMBL8186011 0.89 TGM2 (0.50) TSHRTGM2NOD1HDAC2MME
SCHEMBL8847213 0.87 TGM2 (0.52) TSHRTGM2NOD1HDAC2ZDHHC20
SCHEMBL10935228 0.86 NOD1 (0.54) TGM2NOD1ZDHHC20ZDHHC2FOLH1
SCHEMBL32679869 0.86 NOD1 (0.54) TGM2NOD1ZDHHC20ZDHHC2FOLH1
SCHEMBL28799295 0.86 NOD1 (0.54) TGM2NOD1ZDHHC20ZDHHC2FOLH1
SCHEMBL138376 0.86 NOD1 (0.54) TGM2NOD1ZDHHC20ZDHHC2FOLH1
SCHEMBL16162466 0.86 NOD1 (0.54) TGM2NOD1ZDHHC20ZDHHC2FOLH1
SCHEMBL27868025 0.86 NOD1 (0.54) TGM2NOD1ZDHHC20ZDHHC2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
EP-4728136-A1 STRENGTH SYNERGY BETWEEN POLYMER AND PAPERMAKING STRENGTH AID Ecolab USA, Inc. (US) 2026-04-22 EP claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-20250340028-A1 CONTACT LENSES WITH SOFTER LENS SURFACES ALCON INC (CH) 2025-11-06 US claimed
US-20250303615-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-10-02 US claimed
EP-1216260-A4 METHOD OF INCREASING RETENTION AND DRAINAGE IN PAPERMAKING USING HIGH MOLECULAR WEIGHT WATER-SOLUBLE ANIONIC OR NONIONIC DISPERSION POLYMERS NALCO CHEMICAL CO (US) 2002-11-13 EP claimed
EP-1218299-A1 ANIONIC AND NONIONIC DISPERSION POLYMERS FOR CLARIFICATION AND DEWATERING NALCO CHEMICAL COMPANY (US) 2002-07-03 EP claimed
EP-1218415-A1 WATER SOLUBLE ANIONIC OR NONIONIC DISPERSION POLYMER NALCO CHEMICAL COMPANY (US) 2002-07-03 EP claimed
EP-1216260-A1 METHOD OF INCREASING RETENTION AND DRAINAGE IN PAPERMAKING USING HIGH MOLECULAR WEIGHT WATER-SOLUBLE ANIONIC OR NONIONIC DISPERSION POLYMERS NALCO CHEMICAL COMPANY (US) 2002-06-26 EP claimed
EP-0888387-B1 PROCESS FOR PRODUCING WATER-SOLUBLE ANIONIC DISPERSION POLYMERS NALCO CHEMICAL CO (US) 2001-10-04 EP claimed
US-6265477-B1 WATER SOLUBILITY BLEND NALCO CHEMICAL COMPANY 2001-07-24 US claimed
WO-2001018064-A1 WATER SOLUBLE ANIONIC OR NONIONIC DISPERSION POLYMER NALCO CHEMICAL COMPANY (US) 2001-03-15 WO claimed
WO-2001017914-A1 ANIONIC AND NONIONIC DISPERSION POLYMERS FOR CLARIFICATION AND DEWATERING NALCO CHEMICAL COMPANY (US) 2001-03-15 WO claimed
WO-2001018063-A1 METHOD OF INCREASING RETENTION AND DRAINAGE IN PAPERMAKING USING HIGH MOLECULAR WEIGHT WATER-SOLUBLE ANIONIC OR NONIONIC DISPERSION POLYMERS NALCO CHEMICAL COMPANY (US) 2001-03-15 WO claimed
EP-0775165-B1 DADMAC/VINYL TRIALKOXYSILANE COPOLYMERS AND THEIR USE IN WASTEWATER TREATMENT NALCO CHEMICAL CO (US) 2000-01-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA TSHR 2876/4885TGM2 901/4885FPR2 1381/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L TSHR 1512/4885TGM2 149/4885FPR2 2928/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA TSHR 3379/4885TGM2 1285/4885FPR2 3289/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ TSHR 1465/4885TGM2 834/4885FPR2 2237/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA TSHR 907/4885TGM2 108/4885FPR2 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.