Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | GLA | P06280 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017997 | 1.00 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29189015 | 0.88 | KDM4E (0.44) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29409509 | 0.88 | KDM4E (0.44) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29409507 | 0.88 | KDM4E (0.44) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL31098796 | 0.84 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28227176 | 0.83 | KDM4E (0.54) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29659072 | 0.82 | L3MBTL1 (0.54) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL1694970 | 0.82 | L3MBTL1 (0.54) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL15110928 | 0.78 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28240790 | 0.75 | TRPV4 (0.43) | L3MBTL1KDM4EALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114487166-B | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-114487166-A | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114487166-B | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114487166-B | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114487166-B | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117756704-A | Intermediate compound and preparation method thereof, and preparation method of 4-trifluoromethyl nicotinic acid and derivative thereof | 帕潘纳(北京)科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117658902-A | Method for preparing 4-trifluoromethyl nicotinic acid | 内蒙古源宏精细化工有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113816901-B | Synthesis method of 4-trifluoromethyl nicotinamide | 淮北龙溪生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-114487166-A | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114487166-A | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114487166-A | Method for detecting content of 2, 6-dihydroxy-3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114455557-A | Method for recovering phosphorus oxychloride in chlorination reaction of hydroxyl compound | 江苏中旗科技股份有限公司 | 2022-05-10 | — | — | CN | disclosed |